ASA 07-4, Issue No. 121, August 31, 2007

Dr. Jan Medema's article "The Myth of Dusty Agent" written for the ASA Newsletter 07-1 and the response written by Dr. Benjamin Garrett for ASA Newsletter 07-2, highlighted misconceptions which continue to plague users across the broad protection sphere.
          ASA intends to follow-up the preceding with a series of articles on the protection disciplines. These articles will surface, highlight and challenge "conventional wisdom" which appears to be based more on fallacy, hearsay and the not invented here (NIH) syndrome, than on science and common sense. For this article on skin decontamination and the issue of time, our panel consists of Murray Hamilton, PhD, CBW Programs, University of Denver Research Institute; Barbara Price, PhD, ASA/CBMTS/ICBPS; Nayla Feghali PE, Senior Director Healthcare Decontamination, E-Z-EM; Phillip O'Dell, original licensee RSDL and J. Garfield Purdon PhD, Decontamination Hazard Research, DRDC, Suffield.

Skin Decontamination:
A Critical
Medical Countermeasure

          Historically, the focus of skin decontamination has been the immediate removal of chemical warfare agents (CWA) by adsorbent powders, such as Fuller's Earth. With the modern emphasis on antidotes and other medical treatments, does skin decontamination still have a role as a countermeasure? If the CWAs are neutralized by skin decontamination, is delayed application of neutralizing decontaminants beneficial?

Full Article

As we again approach the regular worldwide flu season, questions remain on what impact H5N1 will have on our increasingly better but not sufficiently prepared health systems. Dr. Ryabchikova provides our ASA family of readers a comprehensive review of the pathology involved and terminology used across the professional sphere. She first presented this information at CBMTS-Industry V.

The Pathology of Avian Influenza
in Birds and Animals:
An Analytical Review

Elena I. Ryabchikova,
Tatyana N. Getmanova

State Research Center of Virology and Biotechnology "Vector". Koltsovo, Novosibirsk region, 630559 Russia

Analysis of the published scientific papers containing data on H5N1 avian influenza gross anatomy, histopathology and the virus nucleoprotein antigen presence has been performed. Common features of the gross anatomy in birds and susceptible mammalian species are presented. Main light macroscopic findings in chicks and other birds and immunohistochemical data on H5N1 influenza virus antigen presence in different cells in birds are given. Pathohistological features and data on H5N1 virus antigen occurence in mice having respiratory and neurological forms of the infection are presented; and, ferrets and non-human primate data are presented. Our analysis showed that infection of the endothelium is a common feature of H5N1 avian influenza in birds, but mammalian species do not show presence of the virus antigen in these cells. Infection of the endothelial cells may play a crucial role in pathogenesis of severe H5N1 influenza virus disease in birds.

Full Article

In Memoriam:

Alsoph Henry Corwin

by Benjamin C. Garrett

          Alsoph H. Corwin died April 30, 2007. He was 99. Corwin spent his professional career on the chemistry faculty of Johns Hopkins University, Baltimore, Maryland, and is well remembered for his contributions as a researcher, educator, and mentor. His studies of the biological toxin ricin make his career relevant to the chemical-biological defense community.

          A native of Marietta, Ohio, Corwin was a 1928 graduate of Marietta College. His academic achievements at Marietta College earned him membership in Phi Beta Kappa, and he would later receive an honorary doctorate from that college, along with induction into its Hall of Fame. Corwin earned his doctorate in chemistry from Harvard University in 1932, where he studied under James Bryant Conant1. That same year, Corwin joined the Hopkins faculty, where he remained until his retirement in 1973.

Full Article

an inside look at ASA 07-4

The Professional Library
USAMRICD Change of Command
Consequences of CW Attacks in Iran: Seminar


CBMTS VII: An Update


Second Interdisciplinary Toxicology Congress
Air Travel and disease: A WHO concern
OPCW Academic Forum in The Hague
Crisis Management Symposium, Japan '08
9th CBW Protection Symposium - Gothenburg
ASA Newsletter: from times past
Focal Point News
Steve Bice/MacB/CBMTS/WHO
Toxic effects of peracetic acid used as CW
JMedCBR: Your On-line Journal
Industry Notes:
CB Medical Systems: BAA 07-01
Recent Contracts



For the Professional in Government and Industry with an interest in Nuclear, Biological and Chemical Defense, Disarmament and Verification; Emergency and Disaster Medical Planning; Industrial Health and Safety; and Environmental Protection

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